1.专利情况
|
序号 |
专利名称 |
专利授权号 |
获准国别 |
完成人 |
类型 |
类别 |
|
1 |
一种多肽用于制备预防或治疗脂肪肝病药物的用途 |
ZL201710539987.8 |
中国 |
金亮 |
发明 专利 |
合作完成-第一人 |
|
2 |
一种2型糖尿病的诊断引物及试剂盒、以及非编码RNA分子标志物的应用 |
ZL201910259705.8 |
中国 |
金亮 |
发明 专利 |
合作完成-第一人 |
|
3 |
胰岛长链非编码RNA 1810019D21Rik及其应用 |
ZL201810305264.6 |
中国 |
金亮 |
发明 专利 |
合作完成-第一人 |
|
4 |
口服降糖肽、其脂肪酸衍生物及用途 |
ZL2019107475199 |
中国 |
高向东 |
发明 专利 |
合作完成-第一人 |
|
5 |
多肽及其应用 |
ZL201810408624.5 |
中国 |
高向东 |
发明 专利 |
合作完成-第一人 |
|
6 |
一株高产蛋白酶的巴布维红酵母 |
ZL2018111702966 |
中国 |
储卫华 |
发明 专利 |
合作完成-第一人 |
|
7 |
一种以复合纳米材料为载体的口服给药系统 |
ZL201711334826.1 |
中国 |
邢莹莹 |
发明 专利 |
合作完成-第二人 |
|
8 |
茜草科类型环肽化合物在制备cGAS-STING信号通路激活剂的药物中的应用 |
ZL 2020 1 0347027.3 |
中国 |
王琛 |
发明 专利 |
合作完成-第二人 |
|
9 |
一种土鳖虫多糖的结构及其用途 |
ZL201910987685.6 |
中国 |
周长林 |
发明 专利 |
合作完成-第一人 |
|
10 |
用于检测三甲胺产生基因的引物对及试剂盒 |
ZL201811203027.5 |
中国 |
李菁 |
发明 专利 |
合作完成-第一人 |
|
11 |
用于检测丁酸合成基因的引物对及试剂盒 |
ZL201811203026.0 |
中国 |
李菁 |
发明 专利 |
合作完成-第一人 |
|
12 |
干扰素突变体及干扰素突变体融合抗体及其制备方法、应用 |
ZL201811027088.0 |
中国 |
张娟 |
发明 专利 |
合作完成-第一人 |
|
13 |
抗菌多肽Pb2-1或PCL-1及其制备方法和应用 |
ZL201910787413.1 |
中国 |
周长林 |
发明 专利 |
合作完成-第一人 |
|
14 |
一种具有免疫检查点拮抗活性的多肽及其应用 |
ZL201810912936.X |
中国 |
徐寒梅 |
发明 专利 |
合作完成-第一人 |
|
15 |
基质金属蛋白酶抑制性多肽金纳米颗粒组合物及其应用、制备方法 |
CN201811503478.0 |
中国 |
薛建鹏 |
发明 专利 |
合作完成-第一人 |
|
16 |
新型罗汉果苷衍生物及其用途 |
ZL201810866066.7 |
中国 |
吴旭日 |
发明 专利 |
合作完成-第一人 |
|
17 |
抗PD-1单克隆抗体及其应用 |
ZL201810108897.8 |
中国 |
邱郑 |
发明 专利 |
合作完成-第一人 |
|
18 |
一种枸杞叶有效成分胶囊及其制备方法 |
ZL20191132899.X |
中国 |
张玉彬 |
发明 专利 |
合作完成-第一人 |
|
19 |
麦冬皂苷D在制备治疗代谢综合征药物上的应用 |
ZL202010371078.X |
中国 |
刘畅 |
发明 专利 |
合作完成-第二人 |
|
20 |
一种脑部靶向转铁蛋白受体的单链抗体及应用 |
ZL201710332943.8 |
中国 |
刘煜 |
发明 专利 |
合作完成-第一人 |
|
21 |
HIGH-ACTIVITY LONG-ACTING HYPOGLYCEMIC FUSION PROTEIN AS WELL AS PREPARATION METHOD AND MEDICAL APPLICATION THEREOF |
US11078250B2 |
美国 |
谭树华 |
发明 专利 |
合作完成-第一人 |
2.发表论文、专著情况
|
序号 |
论文或 专著名称 |
作者 |
刊物、出版社名称 |
卷、期 （或章节）、页 |
类型 |
类别 |
|
1 |
Natural killer cell-derived exosomal miR-1249-3p attenuates insulin resistance and inflammation in mouse models of type 2 diabetes |
王颖 |
Signal Transduction and Targeted Therapy |
6(1): 1-13 |
SCI(E) |
a |
|
2 |
Sequence specific integration by the family 1 casposase from Candidatus Nitrosopumilus koreensis AR1 |
陆美玲 |
NUCLEIC ACIDS RESEARCH |
49(17):9938-9952 |
SCI(E) |
a |
|
3 |
DRAMP 3.0: an enhanced comprehensive data repository of antimicrobial peptides |
郑珩 |
Nucleic Acids Res |
Aug 14:gkab651 |
SCI(E) |
a |
|
4 |
The long non-coding RNA beta Faar regulates islet beta-cell function and survival during obesity in mice |
金亮 |
NATURE COMMUNICATIONS |
12(1):3997 |
SCI(E) |
a |
|
5 |
PD-L1 lncRNA splice isoform promotes lung adenocarcinoma progression via enhancing c-Myc activity |
梁宏伟 |
Genome Biol |
22(1):104 |
SCI(E) |
b |
|
6 |
MMP-12 siRNA improves the homeostasis of the small intestine and metabolic dysfunction in high-fat diet feeding-induced obese mice. |
张雯翔 |
Biomaterials |
278: 121183 |
SCI(E) |
b |
|
7 |
The CK1δ/ε-AES axis regulates tumorigenesis and metastasis in colorectal cancer |
王中原 |
Theranostics |
11(9):4421-4435 |
SCI(E) |
a |
|
8 |
miR-23a/b suppress cGAS-mediated innate and autoimmunity |
崔淑方 |
Cellular & Molecular Immunology |
18(5)：1235-1248 |
SCI(E) |
a |
|
9 |
Integrins as attractive targets for cancer therapeutics |
王颖 |
Acta Pharmaceutica Sinica B |
11(9): 2726-2737 |
SCI(E) |
a |
|
10 |
VEGFR2-targeted antibody fused with IFNamut regulates the tumor microenvironment of colorectal cancer and exhibits potent anti-tumor and anti-metastasis activity |
张娟 |
Acta Pharmaceutica Sinica B |
11(2):420-433 |
SCI(E) |
a |
|
11 |
STING inhibitors target the cyclic dinucleotide binding pocket |
王琛 |
Proceedings of the National Academy of Sciences of the United States of America |
118(24):e2105465118 |
SCI(E) |
a |
|
12 |
Reversal of autoimmunity by mixed chimerism enables reactivation of β cells and transdifferentiation of α cells in diabetic NOD mice |
金亮 |
Proc Natl Acad Sci U S A |
117(49):31219-31230 |
SCI(E) |
a |
|
13 |
Cytosolic Protein Delivery for Intracellular Antigen Targeting Using Supercharged Polypeptide Delivery Platform |
高向东 |
Nano Lett. |
21(14):6022-6030 |
SCI(E) |
a |
|
14 |
Polysaccharides catabolism by the human gut bacterium -Bacteroides thetaiotaomicron: advances and perspectives. |
刘玮 |
Crit Rev Food Sci Nutr. |
61(21):3569-3588 |
SCI(E) |
a |
|
15 |
The interaction of SET and protein phosphatase 2A as target for cancer therapy |
王淑珍 |
Biochim Biophys Acta Rev Cancer |
1876(1):188578 |
SCI(E) |
a |
|
16 |
A purified acidic polysaccharide from Sarcandra glabra as vaccine adjuvant to enhance anti-tumor effect of cancer vaccine. |
刘玮 |
Carbohydr Polym. |
263:117967 |
SCI(E) |
a |
|
17 |
The MYEOV-MYC association promotes oncogenic miR-17/93-5p expression in pancreatic ductal adenocarcinoma |
朱娟娟 |
Cell Death & Disease |
|
SCI(E) |
a |
|
18 |
Multifaceted regulation of translation by the epitranscriptomic modification N6-methyladenosine |
周君 |
Critical Reviews in Biochemistry and Molecular Biology |
56(2):137-148 |
SCI(E) |
a |
|
19 |
Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy |
谭树华 |
EBioMedicine |
65:103250 |
SCI(E) |
a |
|
20 |
Diazinon exposure produces histological damage, oxidative stress, immune disorders and gut microbiota dysbiosis in crucian carp (Carassius auratus gibelio) |
汤佳立 |
Environmental Pollution |
269: 116129 |
SCI(E) |
a |
|
21 |
The Alternatively Spliced Isoforms of Key Molecules in the cGAS- STING Signaling Pathway |
王琛 |
Frontiers in Immunology |
12:1-9 |
SCI(E) |
a |
|
22 |
Tumor Immune Microenvironment and Its Related miRNAs in Tumor Progression |
邢莹莹 |
Frontiers in Immunology |
12:Article 624725 |
SCI(E) |
a |
|
23 |
The alternatively spliced isoforms of key molecules in the cGAS-STING signaling pathway |
朱娟娟 |
Frontiers in Immunology |
12:771744 |
SCI(E) |
a |
|
24 |
Perillaldehyde Inhibition of cGAS Reduces dsDNA-Induced Interferon Response |
崔淑方 |
Frontiers in Immunology |
12：655637 |
SCI(E) |
a |
|
25 |
Selective enzymatic α-1,6-monoglucosylation of mogroside IIIE for the bio-creation of α-siamenoside I, a potential high-intensity sweetener |
吴旭日 |
Food Chemistry |
359: 129938. |
SCI(E) |
a |
|
26 |
Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation |
郑禄枫 |
J Med Chem |
64(21):15702-15715. |
SCI(E) |
a |
|
27 |
Structural analysis and binding sites of inhibitors targeting the CD47/SIRPα interaction in anticancer therapy |
马菱蔓 |
Computational and Structural Biotechnology Journal |
19(2021)5494–5503 |
SCI(E) |
b |
|
28 |
Expression, localization and metabolic function of “resurrected” human |
陈建华 |
International Journal of Biological Macromolecules |
175:30-39 |
SCI(E) |
a |
|
29 |
MiR-375 reduces the stemness of gastric cancer cells through triggering ferroptosis |
邢莹莹 |
Stem Cell Research & Therapy |
(2021) 12:325 |
SCI(E) |
b |
|
30 |
Tumour microenvironment-based molecular profiling reveals ideal candidates for high-grade serous ovarian cancer immunotherapy |
叶俊梅 |
Cell Prolif. |
54(3):e12979 |
SCI(E) |
b |
|
31 |
RNF111-facilitated neddylation potentiates cGAS-mediated antiviral innate immune response |
王琛 |
PLOS Pathogens |
17(3)：e1009401 |
SCI(E) |
a |
|
32 |
Sacubitril Ameliorates Cardiac Fibrosis Through Inhibiting TRPM7 Channel |
王全逸 |
Frontiers in Cell and Developmental Biology |
9：760035 |
SCI(E) |
a |
|
33 |
The Phytochemical Rhein Mediates M 6 A-Independent Suppression of Adipocyte Differentiation |
周君 |
Frontiers in Nutrition |
8:756803 |
SCI(E) |
a |
|
34 |
Prebiotic, antioxidant, and immunomodulatory properties of acidic exopolysaccharide from marine Rhodotorula RY1801 |
储卫华 |
Frontiers in Nutrition |
8:710668 |
SCI(E) |
a |
|
35 |
Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy. |
刘畅 |
Drug Delivery |
28(1): 594-606 |
SCI(E) |
a |
|
36 |
Oral delivery of staphylococcal nuclease ameliorates DSS induced ulcerative colitis in mice via degrading intestinal neutrophil extracellular traps |
吴洁 |
Ecotoxicology and Environmental Safety |
215:112161 |
SCI(E) |
a |
|
37 |
Green light exposure aggravates high-fat diet feeding-induced hepatic steatosis and pancreatic dysfunction in male mice |
刘畅 |
Ecotoxicology and Environmental Safety |
225:112802 |
SCI(E) |
a |
|
38 |
QTMP, a Novel Thiourea Polymer, Causes DNA Damage to Exert Anticancer Activity and Overcome Multidrug Resistance in Colorectal Cancer Cells |
马菱蔓 |
Front Oncol |
2021 May 28;11:667689 |
SCI(E) |
b |
|
39 |
MLK3 Is Associated With Poor Prognosis in Patients With Glioblastomas and Actin Cytoskeleton Remodeling in Glioblastoma Cells. |
侯筱宇 |
Front Oncol. |
10:600762. |
SCI(E) |
a |
|
40 |
The Role of Iron in Cancer Progression. |
郑禄枫 |
Front Oncol |
11:778492 |
SCI(E) |
a |
|
41 |
Fluorescein-based monitoring of RNA N6-methyladenosine at single-nucleotide resolution |
周君 |
Journal of Molecular Cell Biology |
13(4):325-328 |
SCI(E) |
a |
|
42 |
Intervention of cGAS-STING signaling in sterile inflammatory diseases |
王琛 |
Journal of Molecular Cell Biology |
|
SCI(E) |
a |
|
43 |
Antioxidant and reducing lipid accumulation effects of rutin in Caenorhabditis elegans. |
储卫华 |
Biofactors |
47(4): 686-693 |
SCI(E) |
a |
|
44 |
Generation of a Novel High-Affinity Antibody Binding to PCSK9 Catalytic Domain with Slow Dissociation Rate by CDR-Grafting, Alanine Scanning and Saturated Site-Directed Mutagenesis for Favorably Treating Hypercholesterolemia |
谭树华 |
Biomedicines |
9(12)：1783- |
SCI(E) |
a |
|
45 |
WPK5, a Novel Kunitz-Type Peptide from the Leech Whitmania pigra Inhibiting Factor XIa, and Its Loop-Replaced Mutant to Improve Potency |
孔毅 |
|
9, 1745. |
SCI(E) |
a |
|
46 |
Prediction of Anticancer Peptides with High Efficacy and Low Toxicity by Hybrid Model Based on 3D Structure of Peptides |
吴旻 |
International Journal of Molecular Sciences |
22(11):5630 |
SCI(E) |
a |
|
47 |
Nanocarrier-based drug delivery for melanoma therapeutics |
张雯翔 |
International Journal of Molecular Sciences |
22:1873 |
SCI(E) |
a |
|
48 |
PPARs-Orchestrated Metabolic Homeostasis in the Adipose Tissue |
刘畅 |
International Journal of Molecular Sciences |
22:8974 |
SCI(E) |
a |
|
49 |
DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of Deinagkistrodon acutus Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor Xia |
孔毅 |
Pharmaceuticals |
14, 966. |
SCI(E) |
a |
|
50 |
Helicobacter pylori induces gastric cancer via down-regulating miR-375 to inhibit dendritic cell maturation |
邢莹莹 |
Helicobacter |
2021;00:e12813.1-13 |
SCI(E) |
a |
|
51 |
Oral multivalent epitope vaccine, based on UreB, HpaA, CAT, and LTB, for prevention and treatment of Helicobacter pylori infection in C57BL / 6 mice |
赵文锋 |
Helicobacter |
26(3):e12807 |
SCI(E) |
a |
|
52 |
LncRNA CTD-3252C9.4 modulates pancreatic cancer cell survival and apoptosis through regulating IFI6 transcription |
潘怡 |
Cancer Cell International |
21(1):433 |
SCI(E) |
a |
|
53 |
The Regulatory Network of cGAS-STING Pathway in Viral Evasion |
王全逸 |
Frontiers in microbiology |
|
SCI(E) |
a |
|
54 |
cGAS-STING pathway: post-translational modifications and functions in sterile inflammatory diseases |
王琛 |
FEBS Journal |
STATE-OF-THE-ART-REVIEW |
SCI(E) |
a |
|
55 |
MSI-1 combats drug-resistant S. aureus by affecting bacterial viability and inhibiting carotenoid pigment production |
周长林 |
Microbiol Res |
27;255:126909 |
SCI(E) |
a |
|
56 |
Gegen Qinlian decoction relieved DSS-induced ulcerative colitis in mice by modulating Th17/Treg cell homeostasis via suppressing IL-6/JAK2/ STAT3 signaling |
李睿岩 |
phytomedicine |
84 (2021) 153519 |
SCI(E) |
a |
|
57 |
Biliary microbial structure of gallstone patients with a history of endoscopic sphincterotomy surgery |
朱娟娟 |
Frontiers in Cellular and Infection Microbiology |
10: 594778 |
SCI(E) |
b |
|
58 |
Design, synthesis and biological evaluations of diverse Michael acceptor-based phenazine hybrid molecules as TrxR1 inhibitors |
陆园园 |
BIOORGANIC CHEMISTRY |
109:104736 |
SCI(E) |
a |
|
59 |
MicroRNA-23b attenuates tau pathology and inhibits oxidative stress by targeting GnT-III in Alzheimer's disease. |
高向东 |
Neuropharmacology. |
196:108671 |
SCI(E) |
a |
|
60 |
Influence of fluconazole administration on gut microbiome, intestinal barrier and immune response in mice |
储卫华 |
Antimicrobial agents and chemotherapy |
65(6): e02552-20 |
SCI(E) |
a |
|
61 |
Neuronal activity-induced SUMOylation of Akt1 by PIAS3 is required for long-term potentiation of synaptic transmission. |
侯筱宇 |
FASEB J. |
35(8):e21769 |
SCI(E) |
a |
|
62 |
A Multi-epitope Peptide rOmp22 Encapsulated in Chitosan-PLGA Nanoparticles as Vaccine Candidate Against Acinetobacter baumannii Infection |
薛建鹏 |
International Journal of Nanomedicine |
16: 1819–1836 |
SCI(E) |
b |
|
63 |
Vascular endothelial growth factor B exerts lipid-lowering effect by activating AMPK via VEGFR1 |
童玥 |
Life Sciences |
276:119401 |
SCI(E) |
a |
|
64 |
Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice |
张玉彬 |
Life Sci |
281(2021):119778 |
SCI(E) |
a |
|
65 |
Convenient Genetic Encoding of Phenylalanine Derivatives through Their α-Keto Acid Precursors |
宋潇达 |
Biomolecules |
11(9):1358 |
SCI(E) |
a |
|
66 |
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis |
邢莹莹 |
Environmental Toxicology |
2021;1–9. |
SCI(E) |
b |
|
67 |
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1 |
郑禄枫 |
Mol Carcinog |
60(6):413-426. |
SCI(E) |
a |
|
68 |
Cysteine-Based Coupling: Challenges and Solutions |
张娟 |
Bioconjugate chemistry |
32(8)：1525-1534 |
SCI(E) |
a |
|
69 |
Survivin suppression heightens BZML-induced mitotic catastrophe to overcome multidrug resistance by removing therapy-induced senescent A549/Taxol cells |
马菱蔓 |
Biochim Biophys Acta Mol Cell Res |
2021 Nov 20;1869(2):119174 |
SCI(E) |
b |
|
70 |
GABAA receptor agonist muscimol rescues inhibitory microcircuit defects in the olfactory bulb and improves olfactory function in APP/PS1 transgenic mice. |
侯筱宇 |
Neurobiol Aging. |
108:47-57 |
SCI(E) |
a |
|
71 |
Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation |
周君 |
RNA Biology |
18(9):1354-1363 |
SCI(E) |
a |
|
72 |
PCL-1, a Trypsin-Resistant Peptide, Exerts Potent Activity Against Drug-Resistant Bacteria |
马菱蔓 |
Probiotics Antimicrob Proteins |
13(5):1467-1480 |
SCI(E) |
a |
|
73 |
Weissella confusa CGMCC 19,308 strain protects against oxidative stress, increases lifespan, and bacterial disease resistance in Caenorhabditis elegans |
储卫华 |
Probiotics and Antimicrobial Proteins |
2021：1-9 |
SCI(E) |
a |
|
74 |
PCL-1, a Trypsin-Resistant Peptide, Exerts Potent Activity Against Drug-Resistant Bacteria |
马菱蔓 |
Probiotics Antimicrob Proteins |
13(5):1467-1480 |
SCI(E) |
a |
|
75 |
An antitumor peptide RS17-targeted CD47, design, synthesis, and antitumor activity |
王颖 |
Cancer Medicine |
10(6):2125-2136 |
SCI(E) |
b |
|
76 |
A phycocyanin derived eicosapeptide attenuates lung fibrosis development. |
欧瑜 |
Eur J Pharmacol |
908:174356 |
SCI(E) |
a |
|
77 |
Sinomenine ameliorates septic acute lung injury in mice by modulating gut homeostasis via aryl hydrocarbon receptor/Nrf2 pathway |
黄凤杰 |
European Journal of Pharmacology |
912 (2021) 174581 |
SCI(E) |
a |
|
78 |
Review: Inhibitory potential of low molecular weight Heparin in cell adhesion; emphasis on tumor metastasis |
何书英 |
European Journal of Pharmacology |
892:173778. |
SCI(E) |
a |
|
79 |
Inhibition of PAD4-mediated NET formation by clamidine prevents diabetes development in nonobese diabetic mice |
吴洁 |
Eur J Pharmacol |
|
SCI(E) |
a |
|
80 |
Biased agonists with less glucagon-like peptide-1 receptor-mediated endocytosis prolong hypoglycaemic effects. |
高向东 |
Eur J Pharmacol. |
907:174203 |
SCI(E) |
a |
|
81 |
An oral GLP-1 and GIP dual receptor agonist improves metabolic disorders in high fat-fed mice. |
高向东 |
Eur J Pharmacol. |
17:174635. |
SCI(E) |
a |
|
82 |
Continuous stimulation of dual-function peptide PGLP-1-VP inhibits the morbidity and mortality of NOD mice through anti-inflammation and immunoregulation |
张艳峰 |
Scientific Reports |
11(1): 3593-3593 |
SCI(E) |
a |
|
83 |
Combination of polysaccharides from Astragalus membranaceus and Codonopsis pilosula ameliorated mice colitis and underlying mechanisms |
刘玮 |
Journal of Ethnopharmacology |
264, 113280 |
SCI(E) |
b |
|
84 |
Study on performance of mimic uricase and its application |
陈建华 |
Analytical and Bioanalytical Chemistry |
413(26):6571-6580 |
SCI(E) |
a |
|
85 |
Identifying metastatic ability of prostate cancer cell lines using native fluorescence spectroscopy and machine learning methods |
薛建鹏 |
Scientific Reports |
11: 2282. |
SCI(E) |
a |
|
86 |
EGLP-1 lowers body weight better than exendin-4 by reducing food intake and increasing basal energy expenditure in diet-induced obese mice |
金亮 |
Experimental Cell Research |
399(1): 112454-112464 |
SCI(E) |
a |
|
87 |
A novel histone deacetylase inhibitor LT-548-133-1 induces apoptosis by inhibiting HDAC and interfering with microtubule assembly in MCF-7 cells |
何书英 |
Investigational new drugs |
39:1222–1231 |
SCI(E) |
a |
|
88 |
Analysis of Differentially Expressed Genes That Aggravate Metabolic Diseases in Depression |
刘畅 |
Life |
11: 1203 |
SCI(E) |
a |
|
89 |
CD4+ CD8αα+ T cells in the gastric epithelium mediate chronic inflammation induced by Helicobacter felis |
邢莹莹 |
Microbial Pathogenesis |
(2021) 159:105151 |
SCI(E) |
a |
|
90 |
Identification of choline-degrading bacteria from healthy human feces and used for screening of trimethylamine (TMA)-lyase inhibitors |
储卫华 |
Microbial Pathogenesis |
152, 104658 |
SCI(E) |
a |
|
91 |
Improved oral delivery of insulin by PLGA nanoparticles coated with 5 β-cholanic acid conjugated glycol chitosan |
金亮 |
BIOMEDICAL MATERIALS |
16(6):064103 |
SCI(E) |
a |
|
92 |
Immunomodulatory effects of platelets on the severity of hand, foot, and mouth disease infected with enterovirus 71. |
郭薇 |
Pediatr Res. |
89(4):814-822 |
SCI(E) |
a |
|
93 |
Influence of butyrate on the pathogenicity of Aeromonas hydrophila |
储卫华 |
Aquaculture Nutrition |
2021;00:1–7. |
SCI(E) |
a |
|
94 |
Efficient whole-cell biosynthesis of L-gulose by coupling mannitol-1-dehydrogenase with NADH oxidase |
吴旭日 |
Enzyme and Microbial Technology |
148: 109815 |
SCI(E) |
a |
|
95 |
“Resurrected” human-source urate oxidase with high uricolytic activity |
陈建华 |
Enzyme and Microbial Technology |
149:109852 |
SCI(E) |
a |
|
96 |
An antitumor peptide RS17-targeted CD47, design, synthesis, and antitumor activity |
王颖 |
Cancer Medicine |
2021, 10(6): 2125-2136 |
SCI(E) |
b |
|
97 |
Potent antibacterial and antibiofilm activities of TICbf-14, a peptide with increased stability against trypsin |
周长林 |
Journal of Microbiology |
(2022) Vol. 60 |
SCI(E) |
a |
|
98 |
Demethylenetetrahydroberberine Protects Dopaminergic Neurons in Mouse Model of Parkinson’s Disease |
张玉彬 |
Chinese Journal of Natural Medicines |
2021, 19(x): 1-10 |
SCI(E) |
a |
|
99 |
Autophagy and cancer treatment: four functional forms of autophagy and their therapeutic applications |
马菱蔓 |
Zhejiang Univ-Sci B (Biomed & Biotechnol) |
online |
SCI(E) |
b |
|
100 |
Regulation of RDN on Th1/ILC1 cell imbalance in HFMD patients caused by EV71 infection. |
郭薇 |
Chin J Nat Med. |
19(3):205-211. |
SCI(E) |
a |
|
101 |
The efficacy and safety of Nivolumab combined with Ipilimumab in the immunotherapy of cancer: a meta-analysis |
张娟 |
Immunopharmacology and Immunotoxicology |
43(3):386-394 |
SCI(E) |
a |
|
102 |
Strategies to Increase the Production of Biosynthetic Riboflavin |
郑珩 |
Mol Biotechnol |
63(10):909-918 |
SCI(E) |
a |
|
103 |
Changes in the gut microbiota: a possible factor influencing peripheral blood immune indexes in non-obese diabetic mice |
吴洁 |
Antonie van Leeuwenhoek |
|
SCI(E) |
a |
|
104 |
Genome mining of secondary metabolites from a marine-derived Aspergillus terreus B12 |
王颖 |
Archives of Microbiology |
203(9):5621-5633 |
SCI(E) |
a |
|
105 |
Establishment and optimization of a high-throughput mimic perfusion model in ambr ® |
曹荣月 |
Biotechnol Lett |
43(2):423-433 |
SCI(E) |
a |
|
106 |
Genome sequence of Aspergillus flavus A7, a marine-derived fungus with antibacterial activity |
王颖 |
Genome |
64(7):719-733 |
SCI(E) |
a |
|
107 |
Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration |
曾科 |
NATURE COMMUNICATIONS |
(2021) 12:2030 |
SCI(E) |
a |
|
108 |
PKM2 controls the degranulation of secondary and tertiary granules in neutrophils by phosphorylating SNAP-23 |
曾科 |
Cell Mol Immunol |
18(8):2048-2050 |
SCI(E) |
a |
|
109 |
Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice. |
陈思禹 |
Gut Microbes |
13(1): 1946369 |
SCI(E) |
a |
|
110 |
Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis- |
张昕 |
Cellular and Molecular Gastroenterology and Hepatology |
12(4):1179–1199 |
SCI(E) |
a |
|
111 |
Phycocyanin-functionalized black phosphorus quantum dots enhance PDT/PTT therapy by inducing ROS and irreparable DNA damage. |
郭长缨 |
BiomaterialSciences |
9:5302-5318 |
SCI(E) |
a |
|
112 |
Targeted Delivery of Drugs and Genes Using Polymer Nanocarriers for Cancer Therapy |
宋明明 |
International Journal of Molecular Sciences |
22：9118 |
SCI(E) |
a |
|
113 |
Natural Polyphenols in Metabolic Syndrome: Protective Mechanisms and Clinical Applications |
陈思禹 |
International Journal of Molecular Sciences |
22(11):6110 |
SCI(E) |
a |
|
114 |
The multiple regulation of metastasis suppressor NM23-H1 in cancer |
郭长缨 |
Life Sciences |
268, 118995-119002 |
SCI(E) |
a |
|
115 |
Crosstalk between macrophages and natural killer cells in the tumor microenvironment |
郭长缨 |
nternational Immunopharmacolog |
12, 108374-108390. |
SCI(E) |
a |
|
116 |
HET0016 attenuates the stemness of breast cancer cells through targeting CYP4Z1 |
奚涛 |
Mol Carcinog |
60(6):413-426. |
SCI(E) |
a |
|
117 |
Development of a chiral HPLC method for the separation and quantification of hydroxychloroquine enantiomers |
陈依军 |
Sci Rep |
11(1):8017 |
SCI(E) |
a |
|
118 |
Efficacy, Pharmacokinetics, Biodistribution and Excretion of a Novel Acylated Long-Acting Insulin Analogue INS061 in Rats |
陈依军 |
Drug Des Devel Ther |
15:3487-3498 |
SCI(E) |
a |
|
119 |
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis. |
奚涛 |
Environ Toxicol |
|
SCI(E) |
a |
|
120 |
Toll-Like Receptors Regulate the Development and Progression of Renal Diseases |
曾科 |
Kidney Dis |
7(1):14-23 |
SCI(E) |
a |
|
121 |
分子伴侣蛋白介导的革兰阴性菌耐酸机制研究进展 |
刘楠 |
中国药科大学学报 |
52(2): 164-170 |
北核 |
a |
|
122 |
线粒体DNA与cGAS-STING固有免疫信号通路的研究前沿 |
王琛 |
四川大学学报（医学版） |
52(3): 387-395 |
北核 |
a |
|
123 |
基质血管组分(SVF)临床分离技术研究 |
金亮 |
中国细胞生物学学报 |
43(1):73-82 |
CSCD |
a |
|
124 |
LncRNA 与肝脏糖脂代谢的研究进展 |
吴洁 |
生物工程学报 |
36(1): 1−13 |
北核 |
a |
|
125 |
LAG-3的免疫学功能及其抗体药物的研究进展 |
曹荣月 |
中国细胞生物学学报 |
2021,43(02):484-492 |
CSCD |
a |
|
126 |
凝血因子Ⅶ及其重组表达新进展 |
曹荣月 |
中国生物工程杂志 |
2021,41(Z1):129-137. |
北核 |
b |
|
127 |
乳腺癌代谢重编程与微环境重塑的研究进展 |
高向东 |
中国药科大学学报 |
52(02):156-163. |
北核 |
a |
|
128 |
信号肽在大肠杆菌分泌系统中的研究与应用进展 |
高向东 |
中国生物工程杂志 |
41(05):87-93 |
北核 |
b |
|
129 |
1型糖尿病治疗研究进展 |
金亮 |
沈阳药科大学学报 |
38(06),643-648 |
北核 |
a |
|
130 |
非编码RNA与胰岛素信号通路关系及其临床应用 |
金亮 |
中国药科大学学报 |
52(03),279-286 |
北核 |
a |
|
131 |
抑制剂对鱼藤酮所致帕金森病秀丽隐杆线虫模型的影响 |
陈松 |
中国药科大学学报 |
52(03):346-351 |
北核 |
a |
|
132 |
PD-L1和VEGF双靶点联合阻断治疗的研究进展 |
徐寒梅 |
中国生物工程杂志 |
41(09):71-77 |
北核 |
a |
|
133 |
重组甜味蛋白Monellin在E.coli中的表达条件及其对ICR小鼠血糖的影响 |
曹荣月 |
中国调味品 |
2021,46(07):1-6 |
北核 |
a |
|
134 |
小开放阅读框编码微肽的研究进展 |
徐寒梅 |
遗传 |
43(08):737-746 |
北核 |
a |
|
135 |
免疫检查点B7-H3表位疫苗的设计及其抗肿瘤活性 |
田浤 |
中国药科大学学报 |
52(04):472-479 |
北核 |
a |
|
136 |
microRNA-23b对Aβ_(25-35)导致神经细胞凋亡的作用及机制研究 |
姚文兵 |
中国药科大学学报 |
52(04):480-486 |
北核 |
a |
|
137 |
染色体外环状DNA的研究进展 |
梁宏伟 |
中国细胞生物学学报 |
43(12) |
CSCD |
a |
|
138 |
肿节风多糖SGP-2的高级结构解析及构效关系研究 |
高向东 |
中国药科大学学报 |
52(05):630-635. |
北核 |
a |