1.专利情况
| 
					 序号  | 
				
					 专利名称  | 
				
					 专利授权号  | 
				
					 获准国别  | 
				
					 完成人  | 
				
					 类型  | 
				
					 类别  | 
			
| 
					 1  | 
				
					 Crystal forms of Demethyleneberberine hydrochloride and preparation method therefor  | 
				
					 US11242340 B2  | 
				
					 美国  | 
				
					 张玉彬  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 2  | 
				
					 抗TNF-a/PD-1双特异性抗体及其应用  | 
				
					 ZL202010870619.3  | 
				
					 中国  | 
				
					 刘煜  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 3  | 
				
					 一种赛门苷 I 的纯化制备方法  | 
				
					 ZL202110544460.0  | 
				
					 中国  | 
				
					 吴旭日  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 4  | 
				
					 盐酸去亚甲基四氢小檗碱晶型及其制备方法  | 
				
					 ZL202010651059.2  | 
				
					 中国  | 
				
					 张玉彬  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 5  | 
				
					 2位取代蒽醌衍生物在制备治疗白色念珠菌感染药物中的应用  | 
				
					 ZL202010849420.2  | 
				
					 中国  | 
				
					 陆园园  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 6  | 
				
					 抗肿瘤靶向融合蛋白、其偶联物及用途  | 
				
					 ZL201811632324.1  | 
				
					 中国  | 
				
					 高向东  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 7  | 
				
					 CPUL1脂质体及其制备方法  | 
				
					 ZL202110493959.3  | 
				
					 中国  | 
				
					 陆园园  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 8  | 
				
					 一种抗菌多肽HF-18及其制备方法和应用  | 
				
					 ZL201910162027.3  | 
				
					 中国  | 
				
					 周长林  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 9  | 
				
					 蓝藻抗病毒蛋白N在制备抗炎药物中的应用  | 
				
					 ZL202010391561.4  | 
				
					 中国  | 
				
					 欧瑜  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 10  | 
				
					 一株具有抗菌抗氧化活性魏斯氏菌菌株及应用  | 
				
					 ZL2020102353022  | 
				
					 中国  | 
				
					 储卫华  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 11  | 
				
					 一种藻蓝蛋白肽在制备抗肺纤维化药物中的应用  | 
				
					 ZL201911264468.0  | 
				
					 中国  | 
				
					 欧瑜  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 12  | 
				
					 一种靶向c-Met的多肽及其应用  | 
				
					 ZL2019112899887  | 
				
					 中国  | 
				
					 徐寒梅  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 13  | 
				
					 抗人ISG15蛋白抗体基因及其利用  | 
				
					 ZL201910038977.5  | 
				
					 中国  | 
				
					 王琛  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 14  | 
				
					 一种EphB2小分子抑制剂及其用途  | 
				
					 ZL202010811142.1  | 
				
					 中国  | 
				
					 王淑珍  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 15  | 
				
					 一种口服降糖肽在制备治疗或预防糖尿病并发心血管疾病药物中的应用  | 
				
					 ZL202010853498.1  | 
				
					 中国  | 
				
					 高向东  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 16  | 
				
					 一种具有抗CD47免疫检查点拮抗活性的多肽RS-17及其应用  | 
				
					 ZL2019112647227  | 
				
					 中国  | 
				
					 徐寒梅  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 17  | 
				
					 一种抗菌多肽SA-2及其制备方法和应用  | 
				
					 ZL202110293357.3  | 
				
					 中国  | 
				
					 周长林  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 18  | 
				
					 一种PD-1靶向阻断肽及其应用  | 
				
					 ZL202010058292.X  | 
				
					 中国  | 
				
					 邱郑  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 19  | 
				
					 一种抑制肿瘤生长的基因工程菌及其构建方法和应用  | 
				
					 ZL2016101450457  | 
				
					 中国  | 
				
					 徐寒梅  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 20  | 
				
					 小分子化合物1-苄基咪唑在治疗乳腺癌中的应用  | 
				
					 CN202110126433.1  | 
				
					 中国  | 
				
					 郑禄枫  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 21  | 
				
					 一种用于多发性骨髓瘤的双特异性抗体及其应用  | 
				
					 202011079622.X  | 
				
					 中国  | 
				
					 张娟  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 22  | 
				
					 一种组合物及其在制备皮肤修复产品中的应用  | 
				
					 ZL202010069646.0  | 
				
					 中国  | 
				
					 欧瑜  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 23  | 
				
					 新型诺西肽糖基化衍生物及其制备方法和应用  | 
				
					 ZL202010921312.1  | 
				
					 中国  | 
				
					 吴旭日  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 24  | 
				
					 ROCK2抑制剂在制备药物中的用途  | 
				
					 ZL201711383699.4  | 
				
					 中国  | 
				
					 张昕  | 
				
					 发明专利  | 
				
					 合作完成-第二人  | 
			
| 
					 25  | 
				
					 尖吻蝮蛇抗凝血因子XI多肽及其应用  | 
				
					 ZL2012111106060.8  | 
				
					 中国  | 
				
					 孔毅  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 26  | 
				
					 抗人DLL4人源化抗体与海兔毒素衍生物MMAE的偶联物及其制备方法与应用  | 
				
					 ZL 202010429398.6  | 
				
					 中国  | 
				
					 吴旻  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 27  | 
				
					 苯磺酰胺类化合物的医药用途及其药物组合物  | 
				
					 ZL202011070259.5  | 
				
					 中国  | 
				
					 王琛  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 28  | 
				
					 一种长链非编码RNA RP11-499F3.2在逆转肿瘤西妥昔单抗耐药治疗中的应用  | 
				
					 ZL201811214096.6  | 
				
					 中国  | 
				
					 徐寒梅  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 29  | 
				
					 一种非编码RNA生物标志物lnc-Wdr5的应用  | 
				
					 ZL202110097928.6  | 
				
					 中国  | 
				
					 金亮  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
| 
					 30  | 
				
					 脐带间充质干细胞在预防病毒感染所致肺部疾病中的应用  | 
				
					 ZL202211002364.4  | 
				
					 中国  | 
				
					 郭薇  | 
				
					 发明专利  | 
				
					 合作完成-第二人  | 
			
| 
					 31  | 
				
					 多肽及其在制备抗神经退行性疾病药物方面的应用  | 
				
					 ZL202110827432.X  | 
				
					 中国  | 
				
					 高向东  | 
				
					 发明专利  | 
				
					 合作完成-第一人  | 
			
	
2.发表论文、专著情况
| 
				 序号  | 
			
				 论文或 专著名称  | 
			
				 作者  | 
			
				 刊物、出版社名称  | 
			
				 卷、期 (或章节)、页  | 
			
				 类型  | 
			
				 类别  | 
		
| 
				 1  | 
			
				 Micropeptide MIAC inhibits the tumor progression by interacting with AQP2 and inhibiting EREG/EGFR signaling in renal cell carcinoma  | 
			
				 徐寒梅  | 
			
				 Molecular Cancer  | 
			
				 
  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 2  | 
			
				 Characterization of urethritis-associated Neisseria meningitidis isolated from men who have sex with women in China  | 
			
				 储卫华  | 
			
				 JOURNAL OF INFECTION  | 
			
				 84(5):e87-e88  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 3  | 
			
				 Trends in insulin resistance: insights into mechanisms and therapeutic strategy  | 
			
				 徐寒梅  | 
			
				 Signal Transduction and Targeted Therapy  | 
			
				 
  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 4  | 
			
				 Anchoring a Xenogeneic Antigen-Guided Immune Activation System to Tumor Cell Membrane for Solid Tumor Treatment  | 
			
				 陈欢  | 
			
				 Advanced functional materials  | 
			
				 32(22) - 2111499.1-2111499.11  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 5  | 
			
				 DRAMP 3.0: an enhanced comprehensive data repository of antimicrobial peptides.  | 
			
				 劳兴珍  | 
			
				 Nucleic Acids Res  | 
			
				 50(D1):D488-D496  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 6  | 
			
				 UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation  | 
			
				 王琛  | 
			
				 Autophagy  | 
			
				 1-17  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 7  | 
			
				 Tailored protein-conjugated DNA nanoplatform for synergistic cancer therapy  | 
			
				 高向东  | 
			
				 Journal of Controlled Release  | 
			
				 346:250-259  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 8  | 
			
				 Erythrocyte-biomimetic nanosystems to improve antitumor effects of paclitaxel on epithelial cancers  | 
			
				 宋明明  | 
			
				 Journal of Controlled Release  | 
			
				 345: 744-754  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 9  | 
			
				 Cancer-related micropeptides encoded by ncRNAs: Promising drug targets and prognostic biomarkers  | 
			
				 徐寒梅  | 
			
				 Cancer Letters  | 
			
				 547:215723  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 10  | 
			
				 Hypoxia-induced lncRNA RBM5-AS1 promotes tumorigenesis via activating Wnt/β-catenin signaling in breast cancer.  | 
			
				 金亮  | 
			
				 Cell Death Dis  | 
			
				 13(2):95.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 11  | 
			
				 Complement induces podocyte pyroptosis in membranous nephropathy by mediating mitochondrial dysfunction  | 
			
				 李丽民  | 
			
				 Cell Death Dis  | 
			
				 13(3):281  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 12  | 
			
				 Combining adoptive NK cell infusion with a dopamine-releasing peptide reduces senescent cells in aged mice  | 
			
				 徐寒梅  | 
			
				 CELL DEATH & DISEASE  | 
			
				 13(4):305  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 13  | 
			
				 Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2  | 
			
				 张昕  | 
			
				 CELL DEATH & DISEASE  | 
			
				 2022, 13(2):138  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 14  | 
			
				 The MYEOV-MYC association promotes oncogenic miR-17/93-5p expression in pancreatic ductal adenocarcinoma  | 
			
				 朱娟娟  | 
			
				 Cell Death & Disease  | 
			
				 13(1): 15  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 15  | 
			
				 Targeted disruption of mitochondria potently reverses multidrug resistance in cancer therapy  | 
			
				 尹骏  | 
			
				 British Journal of Pharmacology  | 
			
				 179(13):3346-3362  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 16  | 
			
				 Obesity-induced miR-455 upregulation promotes adaptive pancreatic β-cell proliferation through the CPEB1/CDKN1B pathway  | 
			
				 金亮  | 
			
				 diabetes  | 
			
				 71(3): 394-411.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 17  | 
			
				 Enzymatic hydrolyzation of mogrosides in Luo Han Guo extract by NKA-adsorbed snailase improves its sensory profile  | 
			
				 吴旭日  | 
			
				 Food Chemistry  | 
			
				 390: 133205  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 18  | 
			
				 METTL3 modulates chromatin and transcription dynamics during cell fate transition  | 
			
				 刘晓敏  | 
			
				 Cellular and Molecular Life Sciences  | 
			
				 79(11):559  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 19  | 
			
				 Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis  | 
			
				 郑禄枫  | 
			
				 CELLULAR AND MOLECULAR LIFE SCIENCES  | 
			
				 79(7):360  | 
			
				 SCI(E)  | 
			
				 b  | 
		
| 
				 20  | 
			
				 Identification of the c-Jun/H19/miR-19/JNK1 cascade during hepatic stellate cell activation. (accepted)  | 
			
				 刘明慧  | 
			
				 Clinical and Translational Medicine.  | 
			
				 
  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 21  | 
			
				 Hordb a comprehensive database of peptide hormones  | 
			
				 劳兴珍  | 
			
				 Scientific Data,  | 
			
				 2022, 9:187  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 22  | 
			
				 Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis  | 
			
				 李菁  | 
			
				 npj Biofilms and Microbiome  | 
			
				 8(1):11  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 23  | 
			
				 ErbB4 in parvalbumin-positive interneurons mediates proactive interference in olfactory associative reversal learning.  | 
			
				 侯筱宇  | 
			
				 Neuropsychopharmacology  | 
			
				 47(7):1292-1303.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 24  | 
			
				 Intervention of cGAS-STING signaling in sterile inflammatory diseases  | 
			
				 王琛  | 
			
				 Journal of Molecular Cell Biology  | 
			
				 14(2):mjac005  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 25  | 
			
				 Identification of a Novel Potent CYP4Z1 Inhibitor Attenuating the Stemness of Breast Cancer Cells through Lead Optimization.  | 
			
				 尹骏  | 
			
				 Journal Of Medicinal Chemistry  | 
			
				 2022 Nov 22.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 26  | 
			
				 Preparation and characterization of 2-deacetyl-3-O-sulfo-heparosan and its antitumor effects via the fibroblast growth factor receptor pathway  | 
			
				 查正其  | 
			
				 International Journal of Biological Macromolecules  | 
			
				 201 (2022) :47–58  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 27  | 
			
				 Heparosan-based self-assembled nanocarrier for zinc(II) phthalocyanine for use in photodynamic cancer therapy  | 
			
				 查正其  | 
			
				 International Journal of Biological Macromolecules  | 
			
				 219 (2022) :31–43  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 28  | 
			
				 A soy glycinin derived octapeptide protects against MCD diet induced non-alcoholic fatty liver disease in mice  | 
			
				 欧瑜  | 
			
				 FOOD SCI HUM WELL  | 
			
				 011(006):1544-1554  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 29  | 
			
				 Obesity and insulin resistance: Pathophysiology and treatment  | 
			
				 童玥  | 
			
				 Drug Discovery Today  | 
			
				 27(3):822-830  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 30  | 
			
				 Synthesis and Evaluation of Antioxidant and Potential Prebiotic Activities of Acetylated and Butyrylated Fructo-Oligosaccharides  | 
			
				 朱卫  | 
			
				 ANTIOXIDANTS  | 
			
				 11(9): 1658.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 31  | 
			
				 Neutrophil Extracellular Traps Caused by Gut Leakage Trigger the Autoimmune Response in Nonobese Diabetic Mice  | 
			
				 吴洁  | 
			
				 Front Immunol  | 
			
				 12:711423  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 32  | 
			
				 Human lung adenocarcinoma CD47 is upregulated by interferon-γ and promotes tumor metastasis  | 
			
				 曾科  | 
			
				 Mol Ther Oncolytics  | 
			
				 25:276-287  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 33  | 
			
				 Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling  | 
			
				 叶俊梅  | 
			
				 Clinical Sci ence (Lond)  | 
			
				 136(22):1711-1730  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 34  | 
			
				 SIRT6 regulates obesity-induced oxidative stress via ENDOG/SOD2 signaling in the heart  | 
			
				 叶俊梅  | 
			
				 Cell Biol Toxicol.  | 
			
				 Online ahead of print  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 35  | 
			
				 Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1  | 
			
				 黄凤杰  | 
			
				 Life Sciences  | 
			
				 310 (2022): 121115  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 36  | 
			
				 Bifunctional fusion protein targeting both FXIIa and FXIa displays potent anticoagulation effects  | 
			
				 孔毅  | 
			
				 Life Sciences  | 
			
				 309 (2022): 121021  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 37  | 
			
				 A bovine milk-derived peptide ameliorates alloxan-injured pancreatic β cells through IRS2/PI3K/Akt signaling.  | 
			
				 欧瑜  | 
			
				 LIFE SCI  | 
			
				 
  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 38  | 
			
				 Inhibitors of protease-activated receptor 4 (PAR4): a review of recent patents (2013–2021)  | 
			
				 孔毅  | 
			
				 Expert Opinion on Therapeutic Patents  | 
			
				 32(2): 153–170  | 
			
				 SCI(E)  | 
			
				 b  | 
		
| 
				 39  | 
			
				 Dynamic Transcriptome Profiling Reveals LncRNA-Centred Regulatory Networks in the Modulation of Pluripotency  | 
			
				 刘晓敏  | 
			
				 Frontiers in Cell and Developmental Biology  | 
			
				 10:880674  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 40  | 
			
				 Demethylzeylasteral attenuates hepatic stellate cell activation and liver fibrosis by inhibiting AGAP2 mediated signaling  | 
			
				 王淑珍  | 
			
				 Phytomedicine  | 
			
				 105: 154349  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 41  | 
			
				 VEGFR2-MICA fusion antibodies enhance immunotherapy effect and synergize with PD-1 blockade  | 
			
				 张娟  | 
			
				 
  | 
			
				 
  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 42  | 
			
				 Berberine Ameliorates Inflammation in Acute Lung Injury via NF-kBNlrp3 Signaling Pathway  | 
			
				 卞筱泓  | 
			
				 FRONTIERS IN NUTRITION  | 
			
				 9:851255  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 43  | 
			
				 Evaluation of Antioxidative and Neuroprotective Activities of Total Flavonoids From Sea Buckthorn (Hippophae rhamnoides L.)  | 
			
				 储卫华  | 
			
				 FRONTIERS IN NUTRITION  | 
			
				 9:861097  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 44  | 
			
				 Endothelial-Specific Molecule 1 Inhibition Lessens Productive Angiogenesis and Tumor Metastasis to Overcome Bevacizumab Resistance  | 
			
				 纪雪梅  | 
			
				 Cancers  | 
			
				 14(22), 5681  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 45  | 
			
				 The multiple effects of REG1 deletion and SNF1 overexpression improved the production of S-adenosyl-l-methionine in Saccharomyces cerevisiae  | 
			
				 马菱蔓  | 
			
				 Microbial Cell Factories  | 
			
				 21(1):174  | 
			
				 SCI(E)  | 
			
				 b  | 
		
| 
				 46  | 
			
				 Recombinant Reg3α prevents islet β-cell apoptosis and promotes β-cell regeneration  | 
			
				 罗晨  | 
			
				 International Journal of Molecular Science  | 
			
				 23(18): 10584  | 
			
				 SCI(E)  | 
			
				 b  | 
		
| 
				 47  | 
			
				 A novel method to purify small RNAs from human tissues for methylation analysis by LC-MS/MS  | 
			
				 梁宏伟  | 
			
				 Front Mol Biosci  | 
			
				 9:949181  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 48  | 
			
				 Strongylocentrotus nudus Eggs Polysaccharide Enhances Macrophage Phagocytosis Against E.coli Infection by TLR4/STAT3 Axis  | 
			
				 樊竑冶  | 
			
				 Frontiers in Pharmacology  | 
			
				 13:807440  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 49  | 
			
				 A Polysaccharide From Eupolyphaga sinensis Walker With Anti-HBV Activities In Vitro and In Vivo  | 
			
				 周长林  | 
			
				 Frontiers in Pharmacology  | 
			
				 2022(13)  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 50  | 
			
				 The roles and targeting options of TRIM family proteins in tumor  | 
			
				 郑禄枫  | 
			
				 Frontiers in pharmacology  | 
			
				 13:999380  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 51  | 
			
				 Engineering of a UDP-Glycosyltransferase for the Efficient Whole-Cell Biosynthesis of Siamenoside I in Escherichia coli  | 
			
				 吴旭日  | 
			
				 Journal of Agricultural and Food Chemistry  | 
			
				 70: 1601-1609  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 52  | 
			
				 储卫华  | 
			
				 FRONTIERS IN CARDIOVASCULAR MEDICINE  | 
			
				 9:986905  | 
			
				 SCI(E)  | 
			
				 a  | 
		|
| 
				 53  | 
			
				 Blocking CD47 Shows Superior Anti-tumor Therapeutic Effects of Bevacizumab in Gastric Cancer  | 
			
				 刘煜  | 
			
				 Frontiers of Pharmacology  | 
			
				 13, 880139  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 54  | 
			
				 MD2 Is a Potential Biomarker Associated with Immune Cell Infiltration in Gliomas  | 
			
				 王淑珍  | 
			
				 FRONTIERS IN ONCOLOGY  | 
			
				 12:854598  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 55  | 
			
				 Research progress on RNA-binding proteins in breast cancer  | 
			
				 郑禄枫  | 
			
				 Frontiers in oncology  | 
			
				 12:974523  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 56  | 
			
				 Genomic Analysis and Antimicrobial Components of M7, an Aspergillus terreus Strain Derived from the South China Sea  | 
			
				 王颖  | 
			
				 Journal of Fungi  | 
			
				 8 (10): 1051  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 57  | 
			
				 Genomic and Chemical Profiling of B9, a Unique Penicillium Fungus Derived from Sponge  | 
			
				 陆园园  | 
			
				 Journal of Fungi  | 
			
				 8 (7): 686  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 58  | 
			
				 Demethyleneberberine blocked the maturation of IL-1Beta in inflammation by inhibiting TLR4-mitochondria signaling.  | 
			
				 李睿岩  | 
			
				 International immunopharmacology  | 
			
				 113:109319  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 59  | 
			
				 Proteomics analysis uncovers plasminogen activator PLAU as a target of the STING pathway for suppression of cancer cell migration and invasion  | 
			
				 丁明  | 
			
				 Journal of Biological Chemistry  | 
			
				 
  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 60  | 
			
				 Lactobacillus salivarius CPU-01 Ameliorates Temozolomide-Induced Intestinal Mucositis by Modulating Gut Microbiota, Maintaining Intestinal Barrier, and Blocking Pro-inflammatory Cytokines  | 
			
				 储卫华  | 
			
				 Probiotics Antimicrob Proteins.  | 
			
				 1–10  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 61  | 
			
				 Weissella confusa CGMCC 19,308 Strain Protects Against Oxidative Stress, Increases Lifespan, and Bacterial Disease Resistance in Caenorhabditis elegans  | 
			
				 储卫华  | 
			
				 Probiotics Antimicrob Proteins.  | 
			
				 14(1):121-129.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 62  | 
			
				 Reprogramming the Biosynthesis of Precursor Peptide to Create a Selenazole-Containing Nosiheptide Analogue  | 
			
				 陈依军  | 
			
				 ACS SYNTHETIC BIOLOGY  | 
			
				 11(1):85-91  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 63  | 
			
				 Therapeutic applications of adipose-derived stromal vascular fractions in osteoarthritis.  | 
			
				 金亮  | 
			
				 World J Stem Cells  | 
			
				 14(10):744-755  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 64  | 
			
				 Silk fibroin hydrolysate improves memory impairment via multi-target function  | 
			
				 高向东  | 
			
				 Journal of Functional Foods  | 
			
				 89, 104942  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 65  | 
			
				 Fragments of a pectin from Arctium lappa L: Molecular properties and intestinal regulation activity  | 
			
				 高向东  | 
			
				 Journal of Functional Food  | 
			
				 88, 104900  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 66  | 
			
				 Gypenoside XLIX Ameliorate High-Fat Diet-Induced Atherosclerosis via Regulating Intestinal Microbiota, Alleviating Inflammatory Response and Restraining Oxidative Stress in ApoE-/- Mice  | 
			
				 储卫华  | 
			
				 Pharmaceuticals  | 
			
				 15, 1056  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 67  | 
			
				 Anti-inflammatory effects of a SERP 30 polysaccharide from the residue of Sarcandra glabra against lipopolysaccharide-induced acute respiratory distress syndrome in mice  | 
			
				 高向东  | 
			
				 Journal of Ethnopharmacology  | 
			
				 293,115,262  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 68  | 
			
				 Integrating transcriptomics and metabolomics analysis on kojic acid combating Acinetobacter baumannii biofilm and its potential roles  | 
			
				 王颖  | 
			
				 Microbiological Research  | 
			
				 254: 126911-126924  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 69  | 
			
				 Myeloid-Specific Pyruvate-Kinase-Type-M2-Deficient Mice Are Resistant to Acute Lung Injury  | 
			
				 曾科  | 
			
				 Biomedicines  | 
			
				 10(5):1193  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 70  | 
			
				 SCFAs improve disease resistance via modulate gut microbiota, enhance immune response and increase antioxidative capacity in the host  | 
			
				 储卫华  | 
			
				 FISH & SHELLFISH IMMUNOLOGY  | 
			
				 120:560-568.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 71  | 
			
				 Prognostic Value and Potential Regulatory Mechanism of H19 in Stomach Adenocarcinoma  | 
			
				 刘明慧  | 
			
				 Journal of Oncology.  | 
			
				 Volume 2022, Article ID 7702626, 12 pages.  | 
			
				 SCI(E)  | 
			
				 b  | 
		
| 
				 72  | 
			
				 Interaction between Plasma Metabolomics and Intestinal Microbiome in db/db Mouse, an Animal Model for Study of Type 2 Diabetes and Diabetic Kidney Disease  | 
			
				 吴洁  | 
			
				 Metabolites  | 
			
				 12(9)  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 73  | 
			
				 Exploring of probiotic potential vaginal lactobacillus isolates from healthy women against Gardnerella vaginalis and Caenorhabditis elegans model testing  | 
			
				 储卫华  | 
			
				 JOURNAL OF APPLIED MICROBIOLOGY  | 
			
				 133(3):1392-1401.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 74  | 
			
				 2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae  | 
			
				 陆园园  | 
			
				 RESEARCH IN MICROBIOLOGY  | 
			
				 173(6-7):103955  | 
			
				 SCI(E)  | 
			
				 b  | 
		
| 
				 75  | 
			
				 Centranthera grandiflore alleviate alcohol-induced oxidative stress and cell apoptosis  | 
			
				 戚微岩  | 
			
				 Chinese Journal of Natural Medicines  | 
			
				 20(7): 1-8  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 76  | 
			
				 Demethylenetetrahydroberberine protects dopaminergic neurons in a mouse model of Parkinson’s disease  | 
			
				 张玉彬  | 
			
				 Chinese Journal of Natural Medicines  | 
			
				 20(2): 111-119  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 77  | 
			
				 Polystyrene nano/microplastics induce microbiota dysbiosis, oxidative damage, and innate immune disruption in zebrafish  | 
			
				 储卫华  | 
			
				 MICROBIAL PATHOGENESIS  | 
			
				 163:105387.  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 78  | 
			
				 An active domain SA2 derived from cystatinSA, and its antifungal activity  | 
			
				 周长林  | 
			
				 Amino Acids  | 
			
				 2022 Nov 4  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 79  | 
			
				 Prediction of cellular targets in diabetic kidney diseases with singlecell transcriptomic analysis of db/db mouse kidneys  | 
			
				 吴洁  | 
			
				 Journal of Cell Communication and Signaling  | 
			
				 
  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 80  | 
			
				 Development and validation of a liquid chromatography‐tandem mass spectrometry method for CPUL1, a novel antitumor candidate compound, and its application to pharmacokinetic studies  | 
			
				 陆园园  | 
			
				 Journal of Separation Science  | 
			
				 45(22)  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 81  | 
			
				 IL-6 protects cardiomyocytes from oxidative stress at the early stage of LPS-induced sepsis  | 
			
				 叶俊梅  | 
			
				 Biochem Biophys Res Commun.  | 
			
				 603:144-152  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 82  | 
			
				 Obesity induced Ext1 reduction mediates the occurrence of NAFLD  | 
			
				 金亮  | 
			
				 Biochem Biophys Res Commun.  | 
			
				 589:123-130  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 83  | 
			
				 Neuroscience Letters  | 
			
				 张玉彬  | 
			
				 Neuroscience Letters  | 
			
				 785 (2022) 136770  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 84  | 
			
				 Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis  | 
			
				 李丽民  | 
			
				 Kidney Dis  | 
			
				 8(4):308-318  | 
			
				 SCI(E)  | 
			
				 b  | 
		
| 
				 85  | 
			
				 Potent antibacterial and antibiofilm activities of TICbf-14, a peptide with increased stability against trypsin  | 
			
				 周长林  | 
			
				 Journal of Microbiology  | 
			
				 60(1):89-99  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 86  | 
			
				 Probiotics for the Treatment of Gastric Diseases  | 
			
				 邢莹莹  | 
			
				 Nutrition and Cancer  | 
			
				 74 (9) :3051-3057  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 87  | 
			
				 A thioredoxin reductase 1 inhibitor pyrano [3,2-a] phenazine inhibits A549 cells proliferation and migration through the induction of reactive oxygen species production  | 
			
				 王颖  | 
			
				 Molecular Biology Reports  | 
			
				 49: 8835–8845  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 88  | 
			
				 Physicochemical Characterization of Berberineloaded Pluronic F127 Polymeric Micelles and In Vivo Evaluation of Hypoglycemic Effect  | 
			
				 黄凤杰  | 
			
				 Journal of Pharmaceutical Innovation  | 
			
				 2022:1-10  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 89  | 
			
				 Antibacterial Activities of Peptide HF18 Against Helicobacter pylori and its Virulence Protein CagA  | 
			
				 周长林  | 
			
				 International Journal of Peptide Research and Therapeutics  | 
			
				 (2022) 28:63  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 90  | 
			
				 A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria.  | 
			
				 朱卫  | 
			
				 Journal of visualized experiments : JoVE  | 
			
				 184(e64201):1-6  | 
			
				 SCI(E)  | 
			
				 a  | 
		
| 
				 91  | 
			
				 纳米制剂在糖尿病创面愈合中的应用研究  | 
			
				 吴洁  | 
			
				 中国药科大学学报  | 
			
				 1:25-31  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 92  | 
			
				 虾青素临床研究现状及其在特医食品开发中的应用前景  | 
			
				 吴洁  | 
			
				 中国海洋药物  | 
			
				 41(4):89-94  | 
			
				 CSCD  | 
			
				 a  | 
		
| 
				 93  | 
			
				 过表达核苷二磷酸激酶对透明质酸产量和相对分子质量的影响  | 
			
				 虞菊萍  | 
			
				 中国药科大学学报  | 
			
				 53(2): 232-238  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 94  | 
			
				 Bay11-7082通过抑制足细胞焦亡减轻膜性肾病组织损伤  | 
			
				 李丽民  | 
			
				 肾脏病与透析肾移植杂志  | 
			
				 31(3): 201-209  | 
			
				 北核  | 
			
				 b  | 
		
| 
				 95  | 
			
				 时间分辨荧光免疫分析法测定人胰岛素生物学活性  | 
			
				 高向东  | 
			
				 药物分析杂志  | 
			
				 42(01): 51-59  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 96  | 
			
				 重组人生长激素原液及注射液中有关物质UPLC分析方法建立  | 
			
				 高向东  | 
			
				 药物分析杂志  | 
			
				 42(01): 41-50  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 97  | 
			
				 金刚纂中木脂素对食管鳞癌细胞的抑制作用  | 
			
				 戚微岩  | 
			
				 中国药科大学学报  | 
			
				 53,1,93-98  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 98  | 
			
				 功能性微肽通量发现和功能验证的研究进展  | 
			
				 徐寒梅  | 
			
				 遗传  | 
			
				 44,6,478-490  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 99  | 
			
				 脯氨酸羟化酶抑制剂FG-4592抑制脂多糖诱导的星形胶质细胞炎症反应.  | 
			
				 侯筱宇  | 
			
				 中国药理学与毒理学杂志  | 
			
				 36(6):410-417  | 
			
				 北核  | 
			
				 b  | 
		
| 
				 100  | 
			
				 SNP-9对Aβ25-35导致bEnd.3细胞损伤的作用及其机制  | 
			
				 陈松  | 
			
				 中国药科大学学报  | 
			
				 53(3):333-339  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 101  | 
			
				 核糖体蛋白的类泛素化修饰及其功能的研究进展  | 
			
				 陈依军  | 
			
				 中国药科大学学报  | 
			
				 53(5):507-517  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 102  | 
			
				 核受体REV-ERBα整合生物钟与能量代谢  | 
			
				 刘畅  | 
			
				 遗传  | 
			
				 
  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 103  | 
			
				 螯合剂类金属Beta-内酰胺酶抑制剂的研究进展  | 
			
				 张洁琳  | 
			
				 中国药科大学学报  | 
			
				 53(4): 410-422  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 104  | 
			
				 肝脏分泌因子与代谢性疾病  | 
			
				 陈思禹  | 
			
				 遗传  | 
			
				 44(10): 853-866  | 
			
				 北核  | 
			
				 a  | 
		
| 
				 105  | 
			
				 生物化学  | 
			
				 郭薇  | 
			
				 人民卫生出版社  | 
			
				 
  | 
			
				 中文专著  | 
			
				 合作完成—第四人  | 
		
| 
				 106  | 
			
				 生物药物分析  | 
			
				 高向东  | 
			
				 人民卫生出版社  | 
			
				 
  | 
			
				 中文专著  | 
			
				 合作完成—第一人  | 
		
| 
				 107  | 
			
				 海洋天然产物化学  | 
			
				 邢莹莹  | 
			
				 浙江大学出版社  | 
			
				 
  | 
			
				 中文专著  | 
			
				 合作完成—第一人  |